Juande Ramos revealed his anger at Tottenham's miserable start to the season following this UEFA Cup defeat, when his side were undermined by Heurelho Gomes's mistake and Jamie O'Hara's red card.

Gomes should have cleared Benoit Assou-Ekotto's back-pass but instead the keeper was caught in possession and brought down Fabio Quagliarella, with Antonio Di Natale scoring from the penalty spot.

Udinese, flying high in second place in Serie A, should have added to their lead at Stadio Friuli but only sealed their 2-0 win late on when Simone Pepe finished off a flowing move.

Ramos, who has overseen Tottenham's worst start to a season in their history, said: "I'm very angry, because I don't like to lose. We lost this match in this competition and now we have to win matches to qualify for the next stage."

Ledley King played in the Group D game so will probably miss Sunday's match against Bolton when bottom-of-the-table Spurs look to gain ground. Adding to Ramos' worries was Jonathan Woodgate being taken off in the second half with an apparent knock. Assou-Ekotto was hauled off before that after a wretched return to the team.

Ramos had dropped £15m summer signing David Bentley from his squad less than 24 hours after the midfielder's outspoken remarks on Spurs' start to the season emerged. "I chose these 18 out of the 20 in the squad," said Ramos. "I don't know what happened before the match. His reaction was normal, the same as the other players who are not playing."

Even without their winger, Tottenham were matching Udinese until Gomes's error, which was harsh as his saves against Wisla Krakow earned a place in the group stages.

Ramos admitted it was the turning point of the game, but he refused to blame his keeper.

"In the first half we played okay but our keeper made a mistake that turned the game totally in the wrong direction for us," said Ramos. "If there was no mistake from Gomes, if we scored the first goal, things would have been different. Of course, this type of mistake can always happen, this is part of football. I still have to support my players and defend them."

O'Hara was dismissed for two mistimed tackles in the same minute, both against Alexis Sanchez.

Ramos now has to lift his players for Bolton after the dressing room was left deflated by another defeat.

"The situation is not very comfortable," he said. "At this moment morale in the dressing room is not in a normal situation, but they know it's possible to win in football and it's possible to lose."

Udinese Handanovic, Motta, Coda, Domizzi, Lukovic, Inler, D'Agostino, Isla, Sanchez, Quagliarella, Di Natale. Subs: Koprivec, Sala, Ferronetti, Pasquale, Obodo, Pepe, Floro Flores.

Tottenham Gomes, Hutton, King, Woodgate, Assou-Ekotto, Lennon, Zokora, Jenas, O'Hara, Bale, Bent. Subs: Cesar, Dawson, Gilberto, Gunter, Modric, Campbell, Giovani.

Referee Felix Brych (Ger)