logo
   Web Issue 3191 July 4 2008   
spacer
Benefit of the doubt: HRT today
KATRINA TWEEDIEMay 26 2008

For years now, conflicting messages and medical confusion have left millions of menopausal women uncertain whether to take hormone replacement therapy. Now, finally, after six years of alarmist reports about the links between HRT, breast cancer and heart disease, last week experts said the drug is actually safe to use.

When the Women's Health Initiative (WHI) report revealed possible dangers in 2002 the numbers of women on HRT halved. But re-analysis of the original findings by experts from around the world who presented their findings at the World Congress on the Menopause in Madrid last week concludes the dangers were exaggerated. Only the older women in the trials, those nearer 70-years-old, had an already increased risk of heart disease due to their age.

But combination oestrogen and progesterone HRT did not raise the risk of heart disease in healthy woman aged 50 to 59. While oestrogen-only HRT, normally reserved for women who have had their wombs removed, cut the risk of heart disease. The experts found that oestrogen and progesterone HRT did slightly increase the risk of breast cancer in this group, but the effect was minimal.

Those against HRT say a slight increase in breast cancer is still too risky, but others believe women can now take the drug in full confidence. Little wonder women experiencing the tumultuous symptoms of menopause will remain uncertain whether HRT really is a safe option.

"There has been a big drop in confidence which is a shame because the bottom line is that women who want to try something for their menopausal symptoms in the early years, it is actually safe," says Dr Heather Currie, a Dumfries-based gynaecologist who runs the Menopause Matters website.

She was at the World Congress on Menopause and says she is delighted the record has now been set straight. "They looked again at each aspect of the trials and time and again it came up that women within 10 years of the menopause have minimal risks and lots of benefits.

"Women can be reassured that it is an option for them because at the moment many are suffering unnecessarily. Breast cancer continues to be the biggest concern for women but they have to be aware it is an association and we can't say that HRT causes breast cancer.

"It may stimulate the growth of cells that are already there, which can then be picked up and treated earlier but HRT doesn't cause cancer. The association is after it has been used for a long time whereas some women only need to take it for a short time to get over the worst phase in their symptoms.

"But other women do suffer symptoms for a long time and if they feel that controlling this is the most important thing then they should be allowed to take it for as long as they want." She added: "There was a huge upset in 2002 but we now have to move on and say that HRT has an important place in managing the menopause alongside other things like lifestyle, exercise and eating healthily."

Many alternative health practitioners believe it is possible to treat the debilitating symptoms of menopause - such as hot flushes, mood swings and irritability - without resorting to HRT at all.

Carol Rogers, a herbalist from Napiers Clinic in Glasgow, treated many women after their GPs stopped prescribing HRT in 2002. "They had nowhere else to go and needed a lot of support," she recalls. "Some were in their sixties and were suddenly taken off HRT so there was a tremendous exacerbation of their symptoms as they went from having the hormones of a 30-year-old to that of a 65-year-old."

Using herbal medicines such as Black Cohosh, which is known to help hot flushes, sage for sweats and Red Clover which mimics oestrogen, herbalists have successfully treated many women. "The time of life is a big change and throws up all sorts of issues and women often need to speak to someone to make sense of their life," says Carol Rogers. "HRT doesn't always treat all the symptoms; it varies in women and not all respond well to HRT so they may need extra help in certain areas. Some women have symptoms so severe that they really need HRT and I would prefer to see it reserved for those women because I think others can get through it naturally."

Dr Keith Spowart, a consultant gynaecologist who runs a menopause clinic at the Western Infirmary in Glasgow, cautiously welcomed last week's findings. "I would never say that any drug is safe, but the concerns were exaggerated and extrapolated from much older women. The public and GPs alike have been in a state of uncertainty for years so this should lead to less confusion."

  • For more information, go to www.menopausematters.co.uk
  • Napiers Clinic 0141 339 5859.


  • © All rights reserved. Reproduction in whole or in part without permission is prohibited.



    Posted by: Morag, Peeblesshire on 9:12am Mon 26 May 08

    I'm surprised it took so long for this conclusion to be reached. The scare stories were obviously exaggerated from the get-go, but to see that one had to have some basic understanding of the statistics involved, and how they were being manipulated to appear to show the "increased risk". It's a shame that so many women were pressurised into stopping an essentially safe and highly beneficial treatment.

    Posted by: Nina, Aberdeenshire on 1:57pm Mon 26 May 08
    In this article Carol Rogers, a herbalist, said that there was nowhere else for women to go and many needed a lot of support (following the upset in 2002 – the American WHI trial early results released).

    As an HRT user and a woman who has read much of the research (BMJ, JAMA etc) over the last 5 years there was support to be found at the website ” Women’s Health Concern”, affiliated to the British Menopause Society (medical professionals) and also information on the various International Menopause Society sites. In the past few years the award winning website Menopause Matters has evolved, set up by UK medical professionals and has made an outstanding contribution to inform, keeping women updated on a wide variety of important health issues.

    The issues surrounding the medical trials etc are complicated and easily misinterpreted. It was unfortunate in my view, particularly that the WHI study in America, the main contributor to the debate, recruited so many women years and years beyond menopause, many with serious health issues such as obesity and hypertension.

    Dr Keith Spowart comments “I would never say that any drug is safe”

    Herbal remedies also have the potential for harm, probably equal to any prescribed medicine, bearing in mind that many have never been tested sufficiently in clinical trials and their efficacy is often based on hearsay. I believe it is accurate to say that some warnings were raised by the Committee of Safety of Medicines in the UK regarding Black Cohosh.

    The situation is certainly now improving for women and a better understanding is emerging. Personally I am looking forward to the initial release from the American KEEPS clinical trial examining the potential for cardiac benefit.
    Add your comment
    Please note: to publish your comment you must be registered on this site. If you are already registered, please enter your details below.
    Email:
    Password:
    spacer
     IN YOUR AREA
     
    Herald Appointments - Every Friday
    Travel Shop
    Airport Parking
    Travel Insurance
    Copyright © 2008 Newsquest (Herald & Times) Limited. All Rights Reserved   
    Sitemap :: Circulation :: Syndication :: Advertising :: About Us :: Terms of Use